Introduction

Huntington's Disease is an autosomal dominant genetic disorder characterized by progressive loss of motor control and an increase in involunatry movements typically beginning in the latter part of the third decade of life. The disorder is found on the fourth chromosome and is categorized as a trinucleotide repeat disorder due to the massive numbers of CAG expanded repeats that may be found in the DNA.

Laboratories Investigating Huntington's Disease & the Role of the Blood Brain Barrier

• The Muchowski Laboratory at the University of Washington's Department of Pharmacology